GUANGYI ZHANG

Hello! I am currently a research fellow at both Massachusetts General Hospital and Harvard Medical School. My current work is on liver disease diagnosis, drug discovery, and clinical trials with multimodal clinical data and imaging (e.g., fMRI, CT, US), active learning and human-in-the-loop techniques. I am a co-investigator of the major project funded by an NIH R01 grant led by Prof. Anthony Samir, focusing on precise fibrosis stage diagnosis for Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) population (25% global prevalence). I conduct my research at MGH/MIT Center for Ultrasound Research & Translation (CURT). One of my first-authored preliminary research on biomarker development has been accepted in Nature Communications, and the work has been filed as a provisional patent. I also led research on deep learning-based speed-of-sound estimation for quantitative ultrasound using delayed radio-frequency (RF) data, with applications in non-invasive fatty liver assessment and acoustic-aberration correction to improve liver image quality. One of my projects placed among the top three in the IUS 2026 Challenge.